This content is current only at the time of printing. This document was printed on 30 March 2017. A current copy is located at http://apvma.gov.au/node/19306
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|Mode of action||Nicotinic receptor agonist|
|Target pests||Gastrointestinal parasites|
|Hosts||Cats, dogs, aviary birds, sheep and lambs, pigs and poultry|
|Formulations||Oral solution/suspension, oral tablet, misc. vaccines or anti sera, topical solution/suspension, oral powder, pre-mix, and oral syrup|
|Home vet use||Yes|
|No of Australian Approvals and Registrations||2 active constituents, 85 products|
Levamisole in preparations containing 15 per cent or less of levamisole for the treatment of animals except:
Levamisole for the treatment of animals except:
|Australian Health-based guidance values||
ADI: 0.003 mg/kg bw per day (1974)No Australian ARfD established
- Preliminary dietary intake estimates of residues indicate an exceedance of the ADI.
- Consideration of the need to establish an Australian ARfD to assess acute dietary risks.
- There have been a large number of adverse experience reports in animals (majority in sheep) due to the narrow therapeutic window.
- Levamisole is an important and cost-effective anthelmintic and paraciticide. Barbers Pole vaccination should not be viewed as an alternative to levamisole.
- Pest resistance to levamisole is known to have developed in cattle and sheep. It is said to be less efficacious in wool production in some regions due to resistance. However, this chemical is still considered important where drench resistance to other chemicals has developed.