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This publication provides a summary of the data reviewed and an outline of the regulatory considerations for the proposed registration of Bollgard II Cotton Event 15985, which contains the new active constituent Bacillus thuringiensis var. kurstaki delta-endotoxins as produced by the Cry1Ac and Cry2Ab genes and their controlling sequences. The product is proposed to be used for the control of cotton bollworm and native budworm in cotton.