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Second generation anti-coagulant rodenticides—priority 2
|Chemical class||Anticoagulant rodenticides—group includes brodifacoum, bromadiolone, difenacoum, difethialone, and flocoumafen|
|CAS Number||Brodifacoum (56073-10-0), Bromadiolone (28772-56-7), Difenacoum (56073-07-5), Difethialone (104653-34-1), Flocoumafen (90035-08-8)|
|Mode of action||Anticoagulant|
|Hosts||Agricultural, industrial and domestic premises|
|Formulations||Bait, liquid concentrate, pellet, sachet, bait concentrate, block (inc stick) and wax block|
|Home garden use||Yes|
|No of Australian Approvals and Registrations||
Brodifacoum—10 active constituents, 60 products
Bromadiolone—8 active constituents, 25 products
Difenacoum—3 active constituents, 37 products
Difethialone—1 active constituent, 10 products
Flocoumafen—3 active constituents, 4 products
Brodifacoum—Appendix J, Part 2.
Brodifacoum in preparations containing 0.25 per cent or less of brodifacoum.
Brodifacoum except when included in Schedule 6.
Bromadiolone in preparations containing 0.25 per cent or less of bromadiolone.
Bromadiolone except when included in Schedule 6.
Difenacoum—Appendix J, Part 2.
Difenacoum in preparations containing 0.25 per cent or less of Difenacoum.
Difenacoum except when included in Schedule 6.
Difethialone in rodent baits containing 0.0025 per cent or less of difethialone.
Difethialone except when included in Schedule 6.
Flocoumafen in preparations containing 0.005 per cent or less of flocoumafen.
Flocoumafen except when included in Schedule 6.
|Australian Health-based guidance values||
Brodifacoum: ADI—0.0000005 mg/kg bw per day (1990)
Bromadiolone: ADI—0.000002 mg/kg bw per day (1994)
Difenacoum: No Australian ADI established
Difethialone: ADI—0.0000006 mg/kg bw per day (1993)
Flocoumafen: ADI—0.000001 mg/kg bw per day (1995)
Brodifacoum, bromadiolone, difenacoum and flocoumafen: No Australian ARfD established
Difethialone: ARfD—0.0005 mg/kg bw (2007)
- these chemicals persist in organs of poisoned rodents and present a risk to non-target animals that feed on poisoned animals or carcasses
- use of products in domestic premises, animal production facilities and food production facilities is currently allowed. This presents potential risks to humans, pets and wildlife through accidental poisoning. Around 1400 human exposure incidents to rodent baits are reported to Poisons Information Centres annually
- products are not intended for use in crops or the field, though some labels make it difficult to discern this
- use of liquid formulations is a concern because they are not designed for use in bait stations.
- if the second generation anti-coagulant rodenticides were to be removed then less effective anti-coagulants are available.